The antibody treatment donanemab slows clinical decline by around a third, a large trial confirms.
It delays dementia by 4-7 months, and also causes bleeding and swelling in the brain which killed 3 out of 1,700 participants in the study.
It’s better than nothing I guess but it’s not a particularly good treatment.
Sure, but treatments of something that complex has to start somewhere. It seems to go in the right direction and upcoming treatments may build on that. I am not sure that anyone could have expected after many failures to just find the magical cure that completely cures Alzheimers.
The results regarding amyloid plaques just keep going back and forth over time, I’m very curious how this will ultimately play out. I suppose even if the plaques are a symptom rather than the underlying cause it can still be helpful clearing them away.
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For anyone interested in neuroscience, https://kbin.social/m/neuro was just launched :)