I’ll go first. Mine is the instant knockout drug. Like Dexter’s intramuscular injection that causes someone to immediately lose consciousness. Or in the movie Split where there’s the aerosol spray in your face that makes you instantly unconscious. Or pretty much any time someone uses chloroform.
Not to mention that you really can’t trust the producers to provide a consistently good product. You create a cliffhanger for an otherwise good movie and the sequel just turns out to be garbage. If the show is garbage, at least have the decency to make it garbage from start to finish, Don’t betray long time fans.