Vaccinations could be made less painful by treating skin with a vaccine-laden liquid and using ultrasound to push it into the body

Vaccines can be delivered through the skin using ultrasound. This method doesn’t damage the skin and eliminates the need for painful needles. To create a needle-free vaccine, Darcy Dunn-Lawless at the University of Oxford and his colleagues mixed vaccine molecules with tiny, cup-shaped proteins. They then applied liquid mixture to the skin of mice and exposed it to ultrasound – like that used for sonograms – for about a minute and a half.

  • Zink@programming.devEnglish
    1·
    1 year ago

    That sure sounds annoying. I hope being able to plan ahead for the occasional jab makes it not much of a real issue in your life.

    Does it happen for accidental/“natural” pokes? You mentioned the splinter thing, but if you had a thorn, cactus needle, or even a piece of glass stuck in your skin and pulled it out, would you do alright?

    • abraxas@sh.itjust.worksEnglish
      2·
      1 year ago

      I hope being able to plan ahead for the occasional jab makes it not much of a real issue in your life.

      Basically that. I schedule a day off if I need a jab for any reason, and work from home anyway when I’m miserable the next several days.

      Does it happen for accidental/“natural” pokes? You mentioned the splinter thing, but if you had a thorn, cactus needle, or even a piece of glass stuck in your skin and pulled it out, would you do alright?

      All of those are fine. And unlike a lot of people with my issue, blood doesn’t bother me in the least. Once in a great while I’ve gotten a mild version of that from an insect bite, but the feeling is just completely different.

      Oddly, I think if a needle hurt more and did some tearing, it wouldn’t bother me so much.

      But you’re asking some really thought-provoking questions. I have a lot of food-related texture issues and while this is COMPLETELY different, I’m suddenly wondering if it’s a little more similar than I thought. I do believe there’s a psychological component to it; I haven’t been able to test, but if I were surprised with a needle jab outside of a medical setting, I have no idea if it would happen to me or not.

      What I did discover is that my blood pressure doesn’t rise and my heartbeat doesn’t go up in “prep”. I don’t seem to have a stress-rise effect for it to be stress-plummet related. I’m not asking anyone to surprise me with a shot, but I really do wonder what would happen.